+ Noticias

Día del patrimonio
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En una presentación a distancia, realizada este 30 de mayo, el pianista y docente de Pedagogía en Artes Musicales , Luis Velasco Navarro ofreció una puesta en escena que incluyó creaciones de exponentes nacionales como Violeta Parra y Próspero Bisquertt, entre otros.

[fulltext] =>

 

Con una asistencia de 300 personas, y a través de diferentes plataformas digitales, este 30 de mayo la carrera de Pedagogía en Artes Musicales de la U. Mayor realizó un concierto para unirse a las celebraciones por el Día del Patrimonio.

Esta presentación fue llevada a cabo por el pianista y docente de la carrera, Luis Velasco Navarro, quien preparó una concierto en 9 piezas de grandes exponentes de la música chilena, incluyendo a Violeta Parra, Próspero Bisquertt, Horacio Salinas y Víctor Jara, entre otros, y que pudo ser vista a través de Facebook y Youtube. 

En este mismo sentido, la directora de dicha carrera, Lorena Rivera, destacó la propuesta de hacer un recorrido amplio y dar cabida “al rico acervo cultural y musical de nuestro país. Fue también importante incluir la presencia de compositoras destacadas, como el es caso de Juanita San Martín, quien además de contar con una trayectoria que ya es reconocida, es académica de nuestra escuela". 

Cabe destacar que, luego de esta exitosa experiencia, Pedagogía en Artes Musicales se alista para preparar nuevas fechas de concierto, aprovechando los espacios digitales para poder llevar a música y cultura a los hogares del país.

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Imagen noticia
Publicado mircoles, 03 junio 2020 14:19

Académico U. Mayor homenajeó a grandes músicos chilenos en concierto del Día del Patrimonio

En una presentación a distancia, realizada este 30 de mayo, el pianista y docente de Pedagogía en Artes Musicales , Luis Velasco Navarro ofreció una puesta en escena que incluyó creaciones de exponentes nacionales como Violeta Parra y Próspero Bisquertt, entre otros.

INVESTIGACIÓN
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El Dr. Felipe Court, junto a los académicos Bruno Nervi y Margarita Calvo, relata los resultados de la terapia donde utilizan la metformina, una droga ocupada en pacientes diabéticos, como compuesto para reducir efectos secundarios que se producen en pacientes con cáncer, entre los que se cuentan el entumecimiento, el hormigueo y dolor en manos y pies.
 
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La investigación comenzó hace 6 años, cuando el Dr. Felipe Court, director del Centro de Biología Integrativa U. Mayor, comenzó a colaborar con el Dr. Bruno Nervi, quien trabaja en el Centro del Cáncer de la Universidad Católica. A ellos luego se unió la Dra. Margarita Calvo, experta en dolor neuropático. 
 
Así, luego de un tiempo, el equipo que incluía a estudiantes de doctorado, de medicina y varios investigadores, llegó a sus primeros resultados en laboratorio, que apuntaban a que la metformina, una de las drogas más usadas en la regulación de la glicemia en pacientes diabéticos, también tenía un efecto sobre la degeneración neuronal, una de las causas de la neuropatía por quimioterapia.
 
“Encontramos que la metformina, una droga que se utiliza en clínica y no tiene efectos secundarioimportantes en personas sanas, podria reducir el dolor que desarrollan los pacientes con cáncer que son intervenidos con un quimioterapeútico como el oxaliplatino”, explica el Dr. Court, quien agrega que "lo más potente de este hallazgo realizado en modelos preclinicos de laboratorio es que se podría comenzar a probar en humanos por las características de la metformina, ya que no modifica la glicemia en personas sin diabetes y no interfiere con la quimioterapia. De hecho, aumenta su efectividad.
 
El cáncer es una de las principales causas de muerte en el mundo. En Chile, aproximadamente un 26% de las defunciones registradas en 2017 se atribuyeron a diversos tipos de cáncer, siendo la segunda causa de muerte más importante entre las personas de 65 o más años.
 
Ante esto, el académico agrega que "la principal herramienta que tenemos para evitar la mortalidad asociada al cáncer son compuestos conocidos como quimioterapéuticos. Este grupo de fármacos se utilizan por su capacidad de inhibir la proliferación celular y de esta forma evitar el crecimiento tumoral. Sin embargo, en ciertos casos los efectos secundarios que producen las terapias son tan agresivos que limitan su dosis y su tiempo de uso, llevando a la suspensión del tratamiento de quimioterapia e impactando de forma importante en la sobrevida del paciente".
 
Por eso, para optimizar la eficacia del tratamiento y mejorar la calidad de vida del paciente, es imprescindible la identificación de fármacos que prevengan eficientemente los efectos tóxicos de las quimioterapias.
 
“Uno de los efectos secundarios más importantes es la aparición de neuropatías periféricas severas (NPS) que afectan la calidad de vida de los pacientes. Son típicamente dependiente de la dosis, por lo que puede afectar negativamente los resultados oncológicos forzando modificaciones de dosis y/o interrupción prematura del tratamiento”, dice Felipe Court. Y agrega: “La NPS se presenta como un síndrome agudo que aparece poco después a la administración de la quimioterapia, el cual consiste en parestesias distales o periorales y alodinia fría. El segundo efecto se produce por la acumulación de dosis e induce neuropatía periférica y se presenta como una neuropatía sensorial crónica”.
 
El curso de la NPS es impredecible, los síntomas pueden resolverse después de que la quimioterapia es descontinuada, o pueden continuar por años. Los síntomas incluyen entumecimiento, hormigueo y dolor en las manos y los pies. En muchos de los casos, estos síntomas neurosensoriales aumentan en intensidad, pueden persistir en el tiempo y a menudo incluyen dolor neuropático.
 
“Cuando se utiliza oxaliplatino como quimioterapeútico (siendo actualmente el tratamiento de elección para los cánceres gastrointestinales) la tasa de pacientes que informa NPS crónica es de 64-97% con al menos 12% con neuropatía severa”, explica Felipe Court, añadiendo que "la aparición de neuropatía periférica dolorosa durante el tratamiento bien puede requerir reducción de la dosis de quimioterapia o incluso cese, lo que limita los beneficios potenciales contra el cáncer y un gran impacto en la supervivencia del paciente. Los datos clínicos indican que más del 60% de los pacientes tienen que reducir o suspender oxaliplatino debido a este efecto secundario. Se han propuesto varias estrategias para prevenir o tratar la NPS con escaso éxito”.
 
Para leer el paper publicado en la Revista Neurobiology of Pain, ingresa aquí 
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Imagen noticia
Publicado mircoles, 03 junio 2020 04:16

Director del CIB detalla los avances de su investigación sobre la disminución de neuropatías provocadas por quimioterapias

El Dr. Felipe Court, junto a los académicos Bruno Nervi y Margarita Calvo, relata los resultados de la terapia donde utilizan la metformina, una droga ocupada en pacientes diabéticos, como compuesto para reducir efectos secundarios que se producen en pacientes con cáncer, entre los que se cuentan el entumecimiento, el hormigueo y dolor en manos y pies.  

U. Mayor en la prensa

El Mercurio

A 18 días del fin del plazo, más de 58 mil usuarios morosos han firmado convenios con autopistas urbanas

Para Gerardo Ureta, académico de la U. Mayor, este tipo de acuerdos no son buenos, “porque el beneficio genera externalidades en la ciudad, como el uso del auto. Es un mal precedente hacia el futuro, porque no tiene sentido facilitar la utilización de las autopistas y no del transporte público”.

El Mercurio

Especialistas valoran gestión de Mañalich, pero insisten en errores comunicacionales

El integrante de la Mesa Social Covid-19 y Decano de la Facultad de Ciencias de la U. Mayor, Dr. Enrique Paris, califica como una buena medida la permanencia del ministro de Salud, ya que, a su juicio, "el manejo ha sido adecuado".

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Videos destacados

Estudiantes de Enfermería cuentan la experiencia de realizar sus internados en medio de la pandemia.

20 estudiantes y académicos del Conservatorio de Música de la U. Mayor, interpretan "Suite Holberg" de Edvard Grieg.

Opinión

Foto opinión
Opinión// Propuestas para evitar una catástrofe por COVID-19

Carta enviada al Presidente de la República, Sebastián Piñera, por parte de investigadores, académicos, sociedades científicas, médicas y comunicadores, entre ellos el Dr. Rafael González, investigador del Centro de Nanotecnología Aplicada de la U. Mayor.

Redes U.Mayor
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